Water Diabetes in Dogs

Diabetes Insipidus (DI) or Water Diabetes is a rare disorder in dogs that affects their water metabolism, preventing the body from conserving water and releasing too much of it. The condition is characterized by frequent or increased urination, dilute urine (Dull urine), and increase thirst for water.

Unlike Diabetes mellitus, this disease isn’t caused by deficiency of insulin.

There are two major DIs that affect dogs;

  • Neurogenic (Central diabetes insipidus)
  • Nephrogenic diabetes insipidus

Neurogenic DI is caused by the lack of the hormone vasopressin, which regulates the body's retention of water. The hypothalamus in the brain controlled the production and regulation of vasopressin. A dysfunction in its release can be caused by a head injury or also a tumor in the brain. The dysfunction on the production of Vasopressin can also be due to failure in hypothalamus or in the pituitary gland.

Nephrogenic DI is caused by a deficiency of antidiuretic hormone (ADH), which functions to stimulate the capillary muscles and reduce the flow of urine, effectively conserving water for the body's various functions. The cause of Nephrogenic DI is found in the kidneys and their inability to respond appropriately to ADH, allowing too much water from the body to escape into the urine.

This is typically an acquired condition, and may be due to amyloidosis of the kidney, cysts on the kidney, or an imbalance of electrolytes.

Other common symptoms seen in dogs with Diabetes Insipidus may include:

  • Increased urination (polyuria)
  • Increased drinking (polydipsia)
  • Decreased urination with dehydration
  • Houses oiling
  • Poor hair coat

Some of the common causes of DI are;

Inadequate secretion of antidiuretic hormone ADH

  • Congenital defect
  • Unknown causes
  • Trauma
  • Cancer

Renal insensitivity to ADH

  • Congenital
  • Secondary to drugs
  • Secondary to endocrine and metabolic disorders
  • Hyperadrenocorticism - overactive adrenal glands
  • Hypocalemia - low calcium levels in the blood
  • Pyometra - bacterial infection of the uterus
  • Hypercalemia - Increased levels of calcium in the blood

Secondary to renal disease or infection

  • Pyelonephritis - bacterial infection of the kidneys
  • Chronic kidney failure
  • Pyometra - bacterial infection of the uterus

Sometimes, dogs can have a varying issues for urinary accidents at home. Some of these causes shouldn’t be confused with DI.

  • Urinary tract infection
  • Urinary stones
  • Incontinence
  • Urinary Tract Cancer
  • Kidney disease

 You must contact your nearest Vet to for the diagnosis, and offer medications as required.

 

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